{"product_id":"fprl1-polyclonal-antibody-bs66133","title":"FPRL1 Polyclonal Antibody-BS66133","description":"\u003cp\u003eFPRL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66133-50, BS66133-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P25090\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eFPRL1 Polyclonal Antibody-BS66133\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat,\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500-1:2000\u003cbr\u003e\nELISA: 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: FPRL1 Polyclonal Antibody detects endogenous levels of FPRL1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Sample:Liver (Mouse) Lysate at 40 ug\u003cbr\u003e\n Primary: Anti-FPRL1 at 1\/300 dilution, Sample: kidney (Mouse) Lysate at 40 ug\u003cbr\u003e\n Primary: Anti-FPRL1 at 1\/300 dilution\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ALXR; FMLP R I; FMLP R II; FMLP related receptor I; FMLP-R-I; FMLP-R-II; FMLP-related receptor I; FMLPX; Formyl peptide receptor 2; Formyl peptide receptor like 1; Formyl peptide receptor related; Formyl peptide receptor-like 1; FPR 2; FPR2; FPR2_HUMAN; FPR2A; FPRH 1; FPRH 2; FPRH1; FPRH2; FPRL 1; FPRL1; HM63; Lipoxin A4 receptor; LXA4 receptor; LXA4R; N-formyl peptide receptor 2; RFP\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human FPRL1: 51-150\/351\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962723307699,"sku":"BS66133-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962723340467,"sku":"BS66133-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f28ad7b0-fd29-41d7-8964-6891b138d103.jpg?v=1705318564","url":"https:\/\/afsbio.com\/products\/fprl1-polyclonal-antibody-bs66133","provider":"AFSBio Inc.","version":"1.0","type":"link"}