{"product_id":"freac3-polyclonal-antibody-bs65958","title":"FREAC3 Polyclonal Antibody-BS65958","description":"\u003cp\u003eFREAC3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65958-50, BS65958-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q12948\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat,Chicken,Dog, Cow, Horse,\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P,FCM，\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug\/test\u003c\/p\u003e \n\n\u003cp\u003eBackground: Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.\u003cbr\u003e\nInvolvement in disease; Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3); also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.\u003c\/p\u003e\n\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: FREAC3 Polyclonal Antibody detects endogenous levels of FREAC3  protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 57kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Tissue\/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;\u003cbr\u003e\n Antigen retrieval: citrate buffer ( 0.01M, pH 6.0), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min;Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;\u003cbr\u003e\n Incubation: Anti-FOXC1\/FREAC3 Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ARA; FKH L7; FKHL 7; FKHL7; Forkhead (Drosophila) like 7; Forkhead; forkhead box C1; Forkhead box protein C1; Forkhead drosophila homolog like 7; Forkhead like 7; Forkhead related activator 3; Forkhead related protein FKHL7; Forkhead related transcription factor 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FOX C1; FOXC 1; FOXC1; FOXC1_HUMAN; FREAC 3; FREAC-3; FREAC3; homolog-like 7; IGDA; IHG 1; IHG1; IRID 1; IRID1; Iridogoniodysgenesis type 1; Myeloid factor delta.\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human FOXC1\/FREAC3:101-200\/553\u003c\/p\u003e \n\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044022059187,"sku":"BS65958-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044022091955,"sku":"BS65958-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bcae2899-3368-4810-95c0-ec8933a2a034.jpg?v=1707738550","url":"https:\/\/afsbio.com\/products\/freac3-polyclonal-antibody-bs65958","provider":"AFSBio Inc.","version":"1.0","type":"link"}