{"product_id":"frem1-rabbit-pab-a16603","title":"FREM1 Rabbit pAb - A16603","description":"\u003cp\u003eFREM1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A16603-20, A16603-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like\/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor\/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 244kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 72kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 158326\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q5H8C1\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154; FREM1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology \u0026amp; Developmental Biology.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: FREM1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189684854963,"sku":"A16603-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189684887731,"sku":"A16603-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b874ee88-e993-4f56-8d9b-3d0adaa1d26a.png?v=1766432604","url":"https:\/\/afsbio.com\/products\/frem1-rabbit-pab-a16603","provider":"AFSBio Inc.","version":"1.0","type":"link"}