{"product_id":"frizzled-10-fzd10-polyclonal-antibody-bs2601","title":"Frizzled-10 (FZD10) Polyclonal Antibody-BS2601","description":"\u003cp\u003eFrizzled-10 (FZD10) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2601-50, BS2601-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9ULW2\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Receptor for Wnt proteins. Functions in the canonical Wnt\/beta-catenin signaling pathway (By similarity).\u003cbr\u003e\nThe canonical Wnt\/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and\/or in differentiated tissues (Probable).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Frizzled-10 (FZD10) polyclonal antibody detects endogenous levels of Frizzled-10 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 70 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Frizzled-10 (FZD10) polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: EC9706 whole cell lysate (15ug)\u003cbr\u003e\n Lane 2: Hela whole cell lysate (30ug)\u003cbr\u003e\n Lane 3: Myla2059 whole cell lysate (15ug)\u003cbr\u003e\n Lane 4: The Brain tissue lysate of Mouse (30ug)\u003cbr\u003e\n Lane 5: The Brain tissue lysate of Rat (30ug)\u003cbr\u003e\n Lane 6: BV2 whole cell lysate (30ug)\u003cbr\u003e\n Lane 7: PMVEC whole cell lysate (30ug)\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Frizzled-10; Fz-10; hFz10; FzE7; CD350; FZD10\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human Frizzled-10.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987091984563,"sku":"BS2601-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987092017331,"sku":"BS2601-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_de5d0c6c-12ae-4f23-a6bf-cc91d07a2516.jpg?v=1706008983","url":"https:\/\/afsbio.com\/products\/frizzled-10-fzd10-polyclonal-antibody-bs2601","provider":"AFSBio Inc.","version":"1.0","type":"link"}