{"product_id":"frizzled-7-polyclonal-antibody-ra20683","title":"Frizzled-7 Polyclonal Antibody - RA20683","description":"Frizzled-7 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA20683-50, RA20683-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: frizzled class receptor 7 (FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: FZD7; Frizzled-7; Fz-7; hFz7; FzE3\n\nApplications: WB; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 8324\n\nProtein MW (KDa): 64\n\nSWISS: O75084\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120687341747,"sku":"RA20683-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120687374515,"sku":"RA20683-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_78b09a34-6f96-4785-a873-4cead6fb6f2c.png?v=1773369502","url":"https:\/\/afsbio.com\/products\/frizzled-7-polyclonal-antibody-ra20683","provider":"AFSBio Inc.","version":"1.0","type":"link"}