{"product_id":"gα-i-3-rabbit-pab-es5567","title":"Gα i-3 rabbit pAb - ES5567","description":"\u003cp\u003eGα i-3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5567-50, ES5567-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: GNAI3; Guanine nucleotide-binding protein G (k) subunit alpha; G (i) alpha-3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human GNAI3. AA range:31-80\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 41kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2773\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P08754\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Cell membrane; Lipid-anchor. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and\/or the midbody.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202255478963,"sku":"ES5567-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202255511731,"sku":"ES5567-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a5ece597-53f2-4cbe-ba92-25a144dd6cc4.png?v=1767125196","url":"https:\/\/afsbio.com\/products\/g%ce%b1-i-3-rabbit-pab-es5567","provider":"AFSBio Inc.","version":"1.0","type":"link"}