{"product_id":"gaba-a-receptor-α4-polyclonal-antibody-ra25169","title":"GABA A Receptor α4 Polyclonal Antibody - RA25169","description":"\u003cp\u003eGABA A Receptor α4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA25169-50, RA25169-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1) . Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000, IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA (A) receptor subunit alpha-4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2557\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 62\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P48169\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121287487667,"sku":"RA25169-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121287520435,"sku":"RA25169-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_453ccdb7-06a7-4397-aa0d-5dfa905d0eb8.png?v=1773346073","url":"https:\/\/afsbio.com\/products\/gaba-a-receptor-%ce%b14-polyclonal-antibody-ra25169","provider":"AFSBio Inc.","version":"1.0","type":"link"}