{"product_id":"gaba-b-receptor-2-polyclonal-antibody-ra25171","title":"GABA B Receptor 2 Polyclonal Antibody - RA25171","description":"\u003cp\u003eGABA B Receptor 2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA25171-50, RA25171-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: gamma-aminobutyric acid type B receptor subunit 2 (GABBR2) Homo sapiens The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: GABBR2; GPR51; GPRC3B; Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 9568\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 106\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O75899\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121287913651,"sku":"RA25171-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121287946419,"sku":"RA25171-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_36a5b32a-f8d2-48e5-bf56-92148f9ac6e3.png?v=1773346074","url":"https:\/\/afsbio.com\/products\/gaba-b-receptor-2-polyclonal-antibody-ra25171","provider":"AFSBio Inc.","version":"1.0","type":"link"}