{"product_id":"gabaa-ralpha4-polyclonal-antibody-bt-ap03426","title":"GABAA RAlpha4 Polyclonal Antibody - BT-AP03426","description":"\u003cp\u003eGABAA RAlpha4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03426-20, BT-AP03426-50, BT-AP03426-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. GABRA4 encodes Gamma-aminobutyric acid receptor subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in GABRA4.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GABRA4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GABAA Ralpha4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 61640\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P48169; Mouse: Q9D6F4; Rat: P28471\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor subunit alpha-4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2557; Mouse: 14397; Rat: 140675\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240319803571,"sku":"BT-AP03426-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240319836339,"sku":"BT-AP03426-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240319869107,"sku":"BT-AP03426-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4a19166f-7480-4fef-9f3c-bd24f1fc0176.png?v=1769406745","url":"https:\/\/afsbio.com\/products\/gabaa-ralpha4-polyclonal-antibody-bt-ap03426","provider":"AFSBio Inc.","version":"1.0","type":"link"}