{"product_id":"gabarapl2-polyclonal-antibody-e-ab-62383","title":"GABARAPL2 Polyclonal Antibody - E-AB-62383","description":"\u003cp\u003eGABARAPL2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62383-60, E-AB-62383-120, E-AB-62383-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GABARAPL2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GABARAPL2; ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Metabolism,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P60520\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP\/GATE-16 subfamily is essential for a later stage in autophagosome maturation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GABARAPL2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 14kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146241245363,"sku":"E-AB-62383-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146241278131,"sku":"E-AB-62383-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146241310899,"sku":"E-AB-62383-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_31621a38-0d55-4bd6-9b45-5d6a90953fde.png?v=1710292234","url":"https:\/\/afsbio.com\/products\/gabarapl2-polyclonal-antibody-e-ab-62383","provider":"AFSBio Inc.","version":"1.0","type":"link"}