{"product_id":"gad2-polyclonal-antibody-e-ab-60117","title":"GAD2 Polyclonal Antibody - E-AB-60117","description":"\u003cp\u003eGAD2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60117-60, E-AB-60117-120, E-AB-60117-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GAD2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GAD2; GAD65\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Metabolism,Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q05329\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GAD2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:10-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 65kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146040377523,"sku":"E-AB-60117-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146040410291,"sku":"E-AB-60117-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146040443059,"sku":"E-AB-60117-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_52c7a020-b719-4ed9-863f-f39cb246128e.png?v=1710290392","url":"https:\/\/afsbio.com\/products\/gad2-polyclonal-antibody-e-ab-60117","provider":"AFSBio Inc.","version":"1.0","type":"link"}