{"product_id":"galectin-3-mouse-mab-em1237","title":"Galectin-3 Mouse mAb - EM1237","description":"\u003cp\u003eGalectin-3 Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1237-50, EM1237-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: 35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB  1:1, 000-2, 000   IHC 1:100-200  ELISA  10, 000-50, 000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 26kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3958\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P17931\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm,  Nucleus,  Secreted,  Spliceosome\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201992810675,"sku":"EM1237-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201992843443,"sku":"EM1237-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_9e682a02-a167-476c-84d1-c75a12bd6de1.png?v=1767119515","url":"https:\/\/afsbio.com\/products\/galectin-3-mouse-mab-em1237","provider":"AFSBio Inc.","version":"1.0","type":"link"}