{"product_id":"gapdh-monoclonal-antibody-2b8-biotin-conjugated-ra11274","title":"GAPDH Monoclonal Antibody (2B8), Biotin Conjugated - RA11274","description":"\u003cp\u003eGAPDH Monoclonal Antibody (2B8), Biotin Conjugated\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11274-50, RA11274-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; IHC-p\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; MouseMonkey; Dog; Hamster; Rabbit; Pig; sheep; Insect; Yeast\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2597\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04406\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118971543731,"sku":"RA11274-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118971576499,"sku":"RA11274-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_915c40bb-fe1c-4d43-bca0-ea4fb2290bd4.png?v=1773343784","url":"https:\/\/afsbio.com\/products\/gapdh-monoclonal-antibody-2b8-biotin-conjugated-ra11274","provider":"AFSBio Inc.","version":"1.0","type":"link"}