{"product_id":"gapdh-monoclonal-antibody-2b8-ra10493","title":"GAPDH Monoclonal Antibody (2B8) - RA10493","description":"\u003cp\u003eGAPDH Monoclonal Antibody (2B8)\u003c\/p\u003e \n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10493-50, RA10493-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri\u003c\/p\u003e\n\n\u003cp\u003eCondition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC; IHC-p\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; MouseMonkey; Dog; Hamster; Rabbit; Pig; sheep; Insect; Yeast\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2597\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 37\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04406\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119011586227,"sku":"RA10493-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119011618995,"sku":"RA10493-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_19cc132a-34c7-4c77-8d23-78bfd4a6ae32.png?v=1773344246","url":"https:\/\/afsbio.com\/products\/gapdh-monoclonal-antibody-2b8-ra10493","provider":"AFSBio Inc.","version":"1.0","type":"link"}