{"product_id":"gapdh-monoclonal-antibody-bt-mca4853","title":"GAPDH Monoclonal Antibody - BT-MCA4853","description":"\u003cp\u003eGAPDH Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4853-50, BT-MCA4853-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GAPDH\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1A10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GAPDH\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human GAPDH expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 37kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P04406\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: G3PD, GAPD, MGC88685\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2597\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238653059251,"sku":"BT-MCA4853-50","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238653092019,"sku":"BT-MCA4853-100","price":252.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_823d36c0-0a86-4046-98f0-6c33e250eed1.png?v=1769383440","url":"https:\/\/afsbio.com\/products\/gapdh-monoclonal-antibody-bt-mca4853","provider":"AFSBio Inc.","version":"1.0","type":"link"}