{"product_id":"gapdh-polyclonal-antibody-e-ab-40516","title":"GAPDH Polyclonal Antibody - E-AB-40516","description":"\u003cp\u003eGAPDH Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-40516-50, E-AB-40516-100, E-AB-40516-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GAPDH\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: aging associated gene 9 protein; BARS-38; cb609; G3PDH; GAPD; KNC-NDS6; OCAS; p38 component\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat, Zebrafish\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q5XJ10\u003c\/p\u003e\n\n\u003cp\u003eBackground: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant human GAPDH protein expressed by E.coli\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000-2000, IF: 1:100-400\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 40.2kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 36kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43146034020531,"sku":"E-AB-40516-50","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43146034053299,"sku":"E-AB-40516-100","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146034086067,"sku":"E-AB-40516-200","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b8419c29-3180-45b5-a087-77cc1db48790.png?v=1710290226","url":"https:\/\/afsbio.com\/products\/gapdh-polyclonal-antibody-e-ab-40516","provider":"AFSBio Inc.","version":"1.0","type":"link"}