{"product_id":"gata-4-polyclonal-antibody-bt-ap03485","title":"GATA-4 Polyclonal Antibody - BT-AP03485","description":"\u003cp\u003eGATA-4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03485-20, BT-AP03485-50, BT-AP03485-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in GATA4 have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GATA4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GATA-4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44627\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P43694; Mouse: Q08369; Rat: P46152\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GATA4; Transcription factor GATA-4; GATA-binding factor 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2626; Mouse: 14463; Rat: 54254\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240324554931,"sku":"BT-AP03485-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240324587699,"sku":"BT-AP03485-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240324620467,"sku":"BT-AP03485-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8daedad5-bf19-4237-aeb9-34ea98845cab.png?v=1769406821","url":"https:\/\/afsbio.com\/products\/gata-4-polyclonal-antibody-bt-ap03485","provider":"AFSBio Inc.","version":"1.0","type":"link"}