{"product_id":"gata6-monoclonal-antibody-mb66495","title":"GATA6 Monoclonal Antibody-MB66495","description":"\u003cp\u003eGATA6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66495-50, MB66495-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q92908\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA-binding domains, which bind directly to the nucleotide sequence core element GATA . There are six vertebrate GATA proteins, designated GATA-1 to GATA-6 .\u003cbr\u003e\nGATA-6 plays a critical role in endoderm development . It is essential for development of the heart, gut, and other organs . Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm . Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors .\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was purified by immunogen affinity chromatography.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of GATA6 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of GATA6 expression in Hela (A), Hela (B), 293T (C) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Transcription factor GATA-6; GATA-binding factor 6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant human GATA6 protein fragments expressed in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906362314931,"sku":"MB66495-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906362347699,"sku":"MB66495-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5ea94d8a-574c-40fc-a9f4-1db6b98a2766.jpg?v=1702918698","url":"https:\/\/afsbio.com\/products\/gata6-monoclonal-antibody-mb66495","provider":"AFSBio Inc.","version":"1.0","type":"link"}