{"product_id":"gbp2-rabbit-polyclonal-antibody-es10690","title":"GBP2 Rabbit Polyclonal Antibody - ES10690","description":"\u003cp\u003eGBP2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10690-50, ES10690-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein . at AA range: 160-240\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: GBP2,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: GBP2 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Foreskin, Lung, Skin, Spinal cord, Thymus,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 65kD\u003c\/p\u003e\n\n\u003cp\u003eFields: NOD-like receptor signaling pathway\u003c\/p\u003e\n\n\u003cp\u003eFunction: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. induction:By interferon gamma during macrophage activation. Similarity: Belongs to the GBP family.\u003c\/p\u003e \n\n\u003cp\u003eSubcellular Location: Cytoplasm Cytoplasm, perinuclear region Golgi apparatus membrane Membrane, Lipid-anchor Cytoplasmic vesicle GBP2-GBP5 dimers localize to the Golgi apparatus.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: GBP2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Interferon-induced guanylate-binding protein 2, GTP-binding protein 2, GBP-2, HuGBP-2, Guanine nucleotide-binding protein 2\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2634\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: P32456\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q9Z0E6\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q63663\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825499332787,"sku":"ES10690-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825499365555,"sku":"ES10690-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/gbp2-rabbit-polyclonal-antibody-es10690","provider":"AFSBio Inc.","version":"1.0","type":"link"}