{"product_id":"gcm2-polyclonal-antibody-bt-ap15714","title":"GCM2 Polyclonal Antibody - BT-AP15714","description":"\u003cp\u003eGCM2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15714-20, BT-AP15714-50, BT-AP15714-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Developmental biology; Stem cells\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: GCM2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GCM2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O75603; Mouse: O09102\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GCM2; Chorion-specific transcription factor GCMb; hGCMb; GCM motif protein 2; Glial cells missing homolog 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9247; Mouse: 107889\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239147987123,"sku":"BT-AP15714-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239148019891,"sku":"BT-AP15714-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239148052659,"sku":"BT-AP15714-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e7d7d351-6046-4515-bcea-faa6e45a5a2e.png?v=1769389786","url":"https:\/\/afsbio.com\/products\/gcm2-polyclonal-antibody-bt-ap15714","provider":"AFSBio Inc.","version":"1.0","type":"link"}