{"product_id":"gdf-8-polyclonal-antibody-bt-ap03535","title":"GDF-8 Polyclonal Antibody - BT-AP03535","description":"\u003cp\u003eGDF-8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03535-20, BT-AP03535-50, BT-AP03535-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: MSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MSTN\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GDF-8 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 42750\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14793; Mouse: O08689\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MSTN; GDF8; Growth\/differentiation factor 8; GDF-8; Myostatin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2660; Mouse: 17700\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240328782003,"sku":"BT-AP03535-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240328814771,"sku":"BT-AP03535-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240328847539,"sku":"BT-AP03535-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_caef7a8f-95bc-4fd7-9d64-1115cab9d320.png?v=1769406876","url":"https:\/\/afsbio.com\/products\/gdf-8-polyclonal-antibody-bt-ap03535","provider":"AFSBio Inc.","version":"1.0","type":"link"}