{"product_id":"gdf1-polyclonal-antibody-bt-ap09463","title":"GDF1 Polyclonal Antibody - BT-AP09463","description":"\u003cp\u003eGDF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09463-20, BT-AP09463-50, BT-AP09463-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Signal transduction; Stem cells\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: GDF1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Embryonic growth\/differentiation factor 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P27539; Mouse: P20863\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Embryonic growth\/differentiation factor 1;GDF-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2657\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239148413107,"sku":"BT-AP09463-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239148445875,"sku":"BT-AP09463-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239148478643,"sku":"BT-AP09463-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c27df7df-de6a-4534-bf5e-d3bf61262b11.png?v=1769389790","url":"https:\/\/afsbio.com\/products\/gdf1-polyclonal-antibody-bt-ap09463","provider":"AFSBio Inc.","version":"1.0","type":"link"}