{"product_id":"gdf11-monoclonal-antibody-mb66744","title":"GDF11 Monoclonal Antibody-MB66744","description":"\u003cp\u003eGDF11 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66744-50, MB66744-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O95390\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: GDF-11, a member of the transforming growth factor β (TGFβ) superfamily, controls anterior\/posterior patterning of the axial skeleton, regulates organogenesis by controlling expression of GDNF, contributes to the control of Hox gene expression and induces phosphorylation of Smad2. In addition, GDF-11 mediates signaling of Nodal during left-right patterning and development of head structures and inhibits generation of new neurons by neuronal progenitors in the olfactory epithelium.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of GDF11 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of GDF11 expression in GDF11 recombinant protein (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BMP11; Growth\/differentiation factor 11; GDF-11; Bone morphogenetic protein 11; BMP-11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GDF11. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906373685427,"sku":"MB66744-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906373718195,"sku":"MB66744-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4a228c62-51f9-467b-91d9-c1e0476e286b.jpg?v=1702918851","url":"https:\/\/afsbio.com\/products\/gdf11-monoclonal-antibody-mb66744","provider":"AFSBio Inc.","version":"1.0","type":"link"}