{"product_id":"gdpd3-polyclonal-antibody-bs65451","title":"GDPD3 Polyclonal Antibody-BS65451","description":"GDPD3 Polyclonal Antibody\n\nProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers: BS65451-50, BS65451-100\n\nSwiss-Prot: Q7L5L3\n\nHost: Rabbit\n\nGDPD3 Polyclonal Antibody-BS65451\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nReactivity: Human, Mouse, Rat, Dog, Horse,\n\nApplications: IHC-P\n\nAll Applications: IHC-P=1:100-500\n\nBackground: GDE3, also known as glycerophosphodiester phosphodiesterase 3, glycerophosphodiester phosphodiesterase domain containing 2 (GDPD2) or osteoblast differentiation promoting factor (OBDPF), is a 539 amino acid protein belonging to the glycerophosphoryl diester phosphodiesterase family. Possessing glycerophosphoinositol inositolphosphodiesterase activity, GDE3 hydrolyzes glycerophosphoinositol to form inositol 1-phosphate and glycerol, and is suggested to play a role in Actin cytoskeleton remodeling and osteoblast differentiation and growth. A multi-pass membrane protein, GDE3 localizes to cell membrane and cytoplasm, and colocalizes with actin in the cytoskeleton. GDE3 contains one GDPD domain, binds calcium as a cofactor and is encoded by a gene mapping to human chromosome Xq13.1.\n\nPurification and Purity: affinity purified by Protein A\n\nSpecificity: GDPD3 Polyclonal Antibody detects endogenous levels of GDPD3 protein.\n\nBioworld Molecular Weight: 37kDa\n\nNote: For research use only, not for use in diagnostic procedure.\n\nExtra Notes: Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GDPD3) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C., Paraformaldehyde-fixed, paraffin embedded (Human brain glioma)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GDPD3) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C.\n\nAlternative Name: FLJ22603; GDPD 3; GDPD3; GDPD3_HUMAN; Glycerophosphodiester phosphodiesterase domain containing 3; Glycerophosphodiester phosphodiesterase domain-containing protein 3; MGC4171.\n\nImmunogen: KLH conjugated synthetic peptide derived from human GDPD3:101-200\/318 \u003cextracellular\u003e\n\nModification: Unmodified\n\nConjugate: Unconjugated\u003c\/extracellular\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962739527859,"sku":"BS65451-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962739560627,"sku":"BS65451-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ce95f982-4d85-4d8f-87c2-604e17896670.jpg?v=1705318663","url":"https:\/\/afsbio.com\/products\/gdpd3-polyclonal-antibody-bs65451","provider":"AFSBio Inc.","version":"1.0","type":"link"}