{"product_id":"ghr-polyclonal-antibody-bt-ap03560","title":"GHR Polyclonal Antibody - BT-AP03560","description":"\u003cp\u003eGHR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03560-20, BT-AP03560-50, BT-AP03560-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GHR\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GHR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 71500\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P10912; Mouse: P16882; Rat: P16310\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GHR; Growth hormone receptor; GH receptor; Somatotropin receptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2690; Mouse: 14600; Rat: 25235\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240330059955,"sku":"BT-AP03560-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240330092723,"sku":"BT-AP03560-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240330125491,"sku":"BT-AP03560-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cd462bc0-f43b-440d-ba75-c0d19668137c.png?v=1769406897","url":"https:\/\/afsbio.com\/products\/ghr-polyclonal-antibody-bt-ap03560","provider":"AFSBio Inc.","version":"1.0","type":"link"}