{"product_id":"ghr-polyclonal-antibody-e-ab-17322","title":"GHR Polyclonal Antibody - E-AB-17322","description":"\u003cp\u003eGHR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17322-60, E-AB-17322-120, E-AB-17322-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GHR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GH receptor; GH-binding protein; GHBP; GHBP; included; GHR; GHR; Growth hormone binding protein; Growth hormone receptor; Growth hormone receptor precursor; Growth hormone-binding protein; Growth hormone-binding protein; included; Increased responsiveness to growth hormone; included; Serum binding protein; Serum-binding protein; Somatotropin receptor\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell biology, Developmental biology, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P10912\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human GHR\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, ELISA 1:2000-5000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 72 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143858487475,"sku":"E-AB-17322-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143858520243,"sku":"E-AB-17322-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143858553011,"sku":"E-AB-17322-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_85d56268-04cc-4182-a407-b001a898fb8c.png?v=1710242599","url":"https:\/\/afsbio.com\/products\/ghr-polyclonal-antibody-e-ab-17322","provider":"AFSBio Inc.","version":"1.0","type":"link"}