{"product_id":"git2-phospho-tyr392-rabbit-polyclonal-antibody-ra25327","title":"GIT2 (phospho-Tyr392) Rabbit Polyclonal Antibody - RA25327","description":"\u003cp\u003eGIT2 (phospho-Tyr392) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA25327-50, RA25327-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: GIT ArfGAP 2 (GIT2) Homo sapiens This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 84\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight (kDa): 84\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9815\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q14161\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45121295220915,"sku":"RA25327-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121295253683,"sku":"RA25327-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product_087fb84e-9943-4199-bd9a-0aebaa10a2ef.png?v=1787848927","url":"https:\/\/afsbio.com\/products\/git2-phospho-tyr392-rabbit-polyclonal-antibody-ra25327","provider":"AFSBio Inc.","version":"1.0","type":"link"}