{"product_id":"gl-syn-rabbit-pab-es3765","title":"Gl Syn rabbit pAb - ES3765","description":"\u003cp\u003eGl Syn rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3765-50, ES3765-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: GLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Gl Syn. AA range:295-344\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 42kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2752\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P15104\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor. Mainly localizes in the cytosol, with a fraction associated with the cell membrane.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202154193075,"sku":"ES3765-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202154225843,"sku":"ES3765-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6f9bdcb7-0d17-428d-89c9-c4ea684bba15.png?v=1767123156","url":"https:\/\/afsbio.com\/products\/gl-syn-rabbit-pab-es3765","provider":"AFSBio Inc.","version":"1.0","type":"link"}