{"product_id":"gli-1-polyclonal-antibody-bt-ap15737","title":"GLI-1 Polyclonal Antibody - BT-AP15737","description":"\u003cp\u003eGLI-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15737-20, BT-AP15737-50, BT-AP15737-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling; Neuroscience; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GLI1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GLI-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P08151; Mouse: P47806\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GLI-1; Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2735; Mouse: 14632\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239151001779,"sku":"BT-AP15737-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239151034547,"sku":"BT-AP15737-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239151067315,"sku":"BT-AP15737-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1f0df4f3-0a69-45f1-996f-803b83b4add7.png?v=1769389822","url":"https:\/\/afsbio.com\/products\/gli-1-polyclonal-antibody-bt-ap15737","provider":"AFSBio Inc.","version":"1.0","type":"link"}