{"product_id":"glucocorticoid-receptor-polyclonal-antibody-e-ab-70157","title":"Glucocorticoid Receptor Polyclonal Antibody - E-AB-70157","description":"\u003cp\u003eGlucocorticoid Receptor Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70157-60, E-AB-70157-120, E-AB-70157-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Glucocorticoid Receptor\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GCCR; GCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; GR; GRL; Grl1; nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3; group C; member 1 (glucocorticoid receptor)\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P04150,P06536,P06537\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant proteincorresponding to Mouse Glucocorticoid receptor\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000,  IHC 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 91kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 91kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146510729395,"sku":"E-AB-70157-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146510762163,"sku":"E-AB-70157-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146510794931,"sku":"E-AB-70157-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4242db10-91ea-44c3-bd73-bf4241424d94.png?v=1710296639","url":"https:\/\/afsbio.com\/products\/glucocorticoid-receptor-polyclonal-antibody-e-ab-70157","provider":"AFSBio Inc.","version":"1.0","type":"link"}