{"product_id":"glur-δ2-polyclonal-antibody-ra25360","title":"GluR-δ2 Polyclonal Antibody - RA25360","description":"GluR-δ2 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA25360-50, RA25360-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: glutamate ionotropic receptor delta type subunit 2 (GRID2) Homo sapiens The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit\n\nApplications: WB; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 2895\n\nProtein MW (KDa): 113\n\nSWISS: O43424\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121297154227,"sku":"RA25360-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121297186995,"sku":"RA25360-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d660014c-aaeb-4f9f-85c9-213c49e2510d.png?v=1773346181","url":"https:\/\/afsbio.com\/products\/glur-%ce%b42-polyclonal-antibody-ra25360","provider":"AFSBio Inc.","version":"1.0","type":"link"}