{"product_id":"glur4-k858-polyclonal-antibody-bs1649","title":"GluR4 (K858) Polyclonal Antibody-BS1649","description":"\u003cp\u003eGluR4 (K858) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1649-50, BS1649-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P48058\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate\/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate\/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate\/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry (IHC) analyzes of GluR4 (K858) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 100 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: GluR4 (K858) polyclonal antibody detects endogenous levels of GluR4 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Glutamate receptor 4; GluR-4; GluR4; AMPA-selective glutamate receptor 4; GluR-D; Glutamate receptor ionotropic, AMPA 4; GluA4; GRIA4; GLUR4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 850-900 of Human GluR4.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939267940531,"sku":"BS1649-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939267973299,"sku":"BS1649-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_37b39199-b649-4cc8-bf8d-00985c94e43b.jpg?v=1704545681","url":"https:\/\/afsbio.com\/products\/glur4-k858-polyclonal-antibody-bs1649","provider":"AFSBio Inc.","version":"1.0","type":"link"}