{"product_id":"glur4-phospho-ser862-polyclonal-antibody-ra25355","title":"GluR4 (phospho Ser862) Polyclonal Antibody - RA25355","description":"GluR4 (phospho Ser862) Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA25355-50, RA25355-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: glutamate ionotropic receptor AMPA type subunit 4 (GRIA4) Homo sapiens Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA-\u0026gt;GGA; R-\u0026gt;G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\n\nAlternative Names: GRIA4; GLUR4; Glutamate receptor 4; GluR-4; GluR4; AMPA-selective glutamate receptor 4; GluR-D; Glutamate receptor ionotropic; AMPA 4; GluA4\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 2893\n\nProtein MW (KDa): 100\n\nSWISS: P48058\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121296826547,"sku":"RA25355-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121296859315,"sku":"RA25355-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_aadb8a11-e5f6-461e-9768-b4f1f7a8eb47.png?v=1773346176","url":"https:\/\/afsbio.com\/products\/glur4-phospho-ser862-polyclonal-antibody-ra25355","provider":"AFSBio Inc.","version":"1.0","type":"link"}