{"product_id":"gmds-polyclonal-antibody-bt-ap09543","title":"GMDS Polyclonal Antibody - BT-AP09543","description":"\u003cp\u003eGMDS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09543-20, BT-AP09543-50, BT-AP09543-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GMDS\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GDP-mannose 4,6 dehydratase\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60547; Mouse: Q8K0C9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GDP-mannose 4,6 dehydratase;EC 4.2.1.47;GDP-D-mannose dehydratase;GMD\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2762\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239152083123,"sku":"BT-AP09543-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239152115891,"sku":"BT-AP09543-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239152148659,"sku":"BT-AP09543-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2d7cfa2d-ca2f-429a-a81f-5c4a7ec918ce.png?v=1769389841","url":"https:\/\/afsbio.com\/products\/gmds-polyclonal-antibody-bt-ap09543","provider":"AFSBio Inc.","version":"1.0","type":"link"}