{"product_id":"gmds-polyclonal-antibody-e-ab-52916","title":"GMDS Polyclonal Antibody - E-AB-52916","description":"\u003cp\u003eGMDS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52916-60, E-AB-52916-120, E-AB-52916-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GMDS\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4; 6 dehydratase; GMD; Gmds; GMDS; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehydrogenase\/reductase family 3E member 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O60547\u003c\/p\u003e\n\n\u003cp\u003eBackground: GDP-mannose 4, 6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3, 5-epimerase, 4-reductase, designated FX in humans (MIM 137020).\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.96 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human GMDS\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133548167347,"sku":"E-AB-52916-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133548200115,"sku":"E-AB-52916-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133548232883,"sku":"E-AB-52916-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a076d8ae-be21-4b8c-8bfc-0c801d6f474e.png?v=1709899910","url":"https:\/\/afsbio.com\/products\/gmds-polyclonal-antibody-e-ab-52916","provider":"AFSBio Inc.","version":"1.0","type":"link"}