{"product_id":"gmnn-monoclonal-antibody-bt-mca2614","title":"GMNN Monoclonal Antibody - BT-MCA2614","description":"\u003cp\u003eGMNN Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2614-50, BT-MCA2614-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GMNN\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2H10G3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GMNN\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human GMNN (AA: FULL 1-209) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 23.6KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O75496\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Gem, MGORS6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 51053\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238522446003,"sku":"BT-MCA2614-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238522478771,"sku":"BT-MCA2614-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_36a95da9-160b-4397-addf-9eea3c5e506c.png?v=1769382153","url":"https:\/\/afsbio.com\/products\/gmnn-monoclonal-antibody-bt-mca2614","provider":"AFSBio Inc.","version":"1.0","type":"link"}