{"product_id":"gna11-polyclonal-antibody-bt-ap15752","title":"GNA11 Polyclonal Antibody - BT-AP15752","description":"\u003cp\u003eGNA11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15752-20, BT-AP15752-50, BT-AP15752-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GNA11\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Guanine nucleotide-binding protein subunit alpha-11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P29992; Mouse: P21278; Rat: Q9JID2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Guanine nucleotide-binding protein subunit alpha-11;G alpha-11;G-protein subunit alpha-11;Guanine nucleotide-binding protein G;y subunit alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2767\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239152312499,"sku":"BT-AP15752-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239152345267,"sku":"BT-AP15752-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239152378035,"sku":"BT-AP15752-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_38f9ae13-6773-4fc9-8b2b-64aaa647b5fc.png?v=1769389843","url":"https:\/\/afsbio.com\/products\/gna11-polyclonal-antibody-bt-ap15752","provider":"AFSBio Inc.","version":"1.0","type":"link"}