{"product_id":"gng5-polyclonal-antibody-bs61200","title":"GNG5 Polyclonal Antibody-BS61200","description":"\u003cp\u003eGNG5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS61200-50, BS61200-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Guanine nucleotide-binding protein G(I)\/G(S)\/G(O) subunit gamma-5; GNG5; GNGT5\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P63218\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Heterotrimeric G proteinsfunction to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus(a photon, pheromone, odorant, hormone or neuro transmitter) while the effectors(e.g., adenylcyclase),which act to generate one ormore intracellula rmessengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits,since these proteins bind and hydrolyze GTP andmost obvously regulate the activity of the beststudied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in diffeent tissues carry structurally distinct members of the γ aswell astheαand β subunits and that preferential associations between members of subunit families increase G protein functional diversity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: GNG5 polyclonal antibody detects endogenous levels of GNG5 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 7 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of GNG5 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate\u003cbr\u003e\nLane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to residues in Human GNG5.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42913839612083,"sku":"BS61200-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42913839644851,"sku":"BS61200-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0ec650c0-c4f6-4ebc-8ef2-9ac660d4a6ff.jpg?v=1703267181","url":"https:\/\/afsbio.com\/products\/gng5-polyclonal-antibody-bs61200","provider":"AFSBio Inc.","version":"1.0","type":"link"}