{"product_id":"gnrhr-polyclonal-antibody-e-ab-15701","title":"GNRHR Polyclonal Antibody - E-AB-15701","description":"\u003cp\u003eGNRHR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-15701-60, E-AB-15701-120, E-AB-15701-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GNRHR\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GnRH receptor; GnRH-R; GNRHR; GNRHR; GNRHR1; Gonadotropin releasing hormone receptor; gonadotropin-releasing hormone (type 1) receptor 1; Gonadotropin-releasing hormone receptor; GRHR; HH7; leutinizing-releasing hormone receptor; lh-rh; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; type I GnRH receptor\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P30968\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.9 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human GNRHR\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000-1:5000, IHC 1:150-1:500\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143815364787,"sku":"E-AB-15701-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143815397555,"sku":"E-AB-15701-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143815430323,"sku":"E-AB-15701-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_581e720f-adf0-4e49-a90b-88eea97b140c.png?v=1710241933","url":"https:\/\/afsbio.com\/products\/gnrhr-polyclonal-antibody-e-ab-15701","provider":"AFSBio Inc.","version":"1.0","type":"link"}