{"product_id":"gpbar1-polyclonal-antibody-e-ab-93270","title":"GPBAR1 Polyclonal Antibody - E-AB-93270","description":"\u003cp\u003eGPBAR1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93270-60, E-AB-93270-120, E-AB-93270-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GPBAR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BG37; TGR5; M-BAR; GPCR19; GPR131\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q8TDU6\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human GPBAR1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 35kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145992437939,"sku":"E-AB-93270-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145992470707,"sku":"E-AB-93270-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145992503475,"sku":"E-AB-93270-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2089e338-af6a-40bd-8d8b-af9e914af8ff.png?v=1710289413","url":"https:\/\/afsbio.com\/products\/gpbar1-polyclonal-antibody-e-ab-93270","provider":"AFSBio Inc.","version":"1.0","type":"link"}