{"product_id":"gpnmb-polyclonal-antibody-bt-ap09590","title":"GPNMB Polyclonal Antibody - BT-AP09590","description":"\u003cp\u003eGPNMB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09590-20, BT-AP09590-50, BT-AP09590-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GPNMB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transmembrane glycoprotein NMB\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14956; Mouse: Q99P91; Rat: Q6P7C7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transmembrane glycoprotein NMB;Transmembrane glycoprotein HGFIN\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10457\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239156342963,"sku":"BT-AP09590-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239156375731,"sku":"BT-AP09590-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239156408499,"sku":"BT-AP09590-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_49eed284-50cb-4d01-9a10-1c8059875977.png?v=1769389886","url":"https:\/\/afsbio.com\/products\/gpnmb-polyclonal-antibody-bt-ap09590","provider":"AFSBio Inc.","version":"1.0","type":"link"}