{"product_id":"gpnmb-rabbit-pab-a14270","title":"GPNMB Rabbit pAb - A14270","description":"\u003cp\u003eGPNMB Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A14270-20, A14270-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 64kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 64kDa\/90-120kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10457\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14956\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NMB; HGFIN; PLCA3; GPNMB\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor immunology, Tumor-associated antigens, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: GPNMB\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189589762227,"sku":"A14270-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189589794995,"sku":"A14270-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_6e995b8e-633e-40ce-baa1-1c4dab6abfda.png?v=1766430451","url":"https:\/\/afsbio.com\/products\/gpnmb-rabbit-pab-a14270","provider":"AFSBio Inc.","version":"1.0","type":"link"}