{"product_id":"gpr143-polyclonal-antibody-bt-ap03696","title":"GPR143 Polyclonal Antibody - BT-AP03696","description":"\u003cp\u003eGPR143 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03696-20, BT-AP03696-50, BT-AP03696-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GPR143\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GPR143 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 43878\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P51810; Mouse: P70259\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4935; Mouse: 18241\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240338612403,"sku":"BT-AP03696-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240338645171,"sku":"BT-AP03696-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240338677939,"sku":"BT-AP03696-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9b23eeb2-88a1-4206-aba7-dfeb6558e9f9.png?v=1769407022","url":"https:\/\/afsbio.com\/products\/gpr143-polyclonal-antibody-bt-ap03696","provider":"AFSBio Inc.","version":"1.0","type":"link"}