{"product_id":"gpt-polyclonal-antibody-e-ab-62774","title":"GPT Polyclonal Antibody - E-AB-62774","description":"\u003cp\u003eGPT Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62774-60, E-AB-62774-120, E-AB-62774-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GPT\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GPT; AAT1; ALT1; GPT1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Metabolism,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P24298\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GPT\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 54kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146261725363,"sku":"E-AB-62774-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146261758131,"sku":"E-AB-62774-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146261790899,"sku":"E-AB-62774-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a45520ef-1294-430a-af37-2adc7e7de75a.png?v=1710292570","url":"https:\/\/afsbio.com\/products\/gpt-polyclonal-antibody-e-ab-62774","provider":"AFSBio Inc.","version":"1.0","type":"link"}