{"product_id":"grem2-polyclonal-antibody-e-ab-90784","title":"GREM2 Polyclonal Antibody - E-AB-90784","description":"\u003cp\u003eGREM2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90784-60, E-AB-90784-120, E-AB-90784-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GREM2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GREM2; CKTSF1B2; DAND3; PRDC; STHAG9; gremlin-2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9H772\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GREM2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 19kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 19kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146574364851,"sku":"E-AB-90784-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146574397619,"sku":"E-AB-90784-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146574430387,"sku":"E-AB-90784-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_dd27319a-df50-4c1d-95a3-2f64a9524672.png?v=1710297683","url":"https:\/\/afsbio.com\/products\/grem2-polyclonal-antibody-e-ab-90784","provider":"AFSBio Inc.","version":"1.0","type":"link"}