{"product_id":"gremlin-2-polyclonal-antibody-bt-ap15779","title":"Gremlin-2 Polyclonal Antibody - BT-AP15779","description":"\u003cp\u003eGremlin-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15779-20, BT-AP15779-50, BT-AP15779-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: GREM2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Gremlin-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H772; Mouse: O88273\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Gremlin-2;Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;Protein related to DAN and cerberus; Gremlin-2; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; Protein related to DAN and cerberus\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 64388; Mouse: 23893\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239158866099,"sku":"BT-AP15779-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239158898867,"sku":"BT-AP15779-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239158931635,"sku":"BT-AP15779-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9acdd0dd-2eac-4c54-b949-983b70086739.png?v=1769389918","url":"https:\/\/afsbio.com\/products\/gremlin-2-polyclonal-antibody-bt-ap15779","provider":"AFSBio Inc.","version":"1.0","type":"link"}