{"product_id":"gremlin-2-rabbit-pab-es8709","title":"Gremlin-2 rabbit pAb - ES8709","description":"\u003cp\u003eGremlin-2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8709-50, ES8709-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; Protein related to DAN and cerberus)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2. AA range:71-120\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 19kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 64388\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9H772\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202390483123,"sku":"ES8709-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202390515891,"sku":"ES8709-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_b1456abd-7efe-4ca5-986d-6065b2fbcef6.png?v=1767128115","url":"https:\/\/afsbio.com\/products\/gremlin-2-rabbit-pab-es8709","provider":"AFSBio Inc.","version":"1.0","type":"link"}