{"product_id":"gria3-rabbit-pab-a13993","title":"GRIA3 Rabbit pAb - A13993","description":"GRIA3 Rabbit pAb\n\nSizes: 20μL, 100μL\n\nCatalogue Numbers: A13993-20, A13993-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA-\u0026gt;GGA; R-\u0026gt;G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.\n\nCategory: Polyclonal Antibodies\n\nApplications: WB, IF\/ICC, ELISA\n\nCross-reactivity: Human, Mouse, Rat\n\nProtein Weight: 101kDa\n\nObserved Molecular Weight: 101kDa\n\nImmunogen: Recombinant protein (or fragment)\n\nSpecies: Human\n\nGeneID: 2892\n\nSWISS: P42263\n\nAlternate Names: GLUR3; GLURC; GluA3; MRX94; MRXSW; GLUR-C; iGluR3; GLUR-K3; GRIA3\n\nSource: Rabbit\n\nIsotype: IgG\n\nPurity: Affinity purification\n\nStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\n\nRecommended Dilutions: WB, 1:500 - 1:1000 IF\/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\n\nResearch Areas: Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Dopamine Signaling in Parkinson's Disease.\n\nNCBI Alias: GRIA3\n\nResearch Use Only","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189581275315,"sku":"A13993-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189581308083,"sku":"A13993-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5cec2521-512f-4005-84c5-96f6f796c823.png?v=1766430224","url":"https:\/\/afsbio.com\/products\/gria3-rabbit-pab-a13993","provider":"AFSBio Inc.","version":"1.0","type":"link"}