{"product_id":"gria4-polyclonal-antibody-e-ab-62775","title":"GRIA4 Polyclonal Antibody - E-AB-62775","description":"\u003cp\u003eGRIA4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62775-60, E-AB-62775-120, E-AB-62775-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GRIA4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: GRIA4; GLUR4; GLUR4C; GLURD; GluA4\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P48058\u003c\/p\u003e\n\n\u003cp\u003eBackground: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA-\u0026gt;GGA; R-\u0026gt;G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human GRIA4 (NP_001070712.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:4000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49kDa\/100kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 101kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146261889203,"sku":"E-AB-62775-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146261921971,"sku":"E-AB-62775-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146261954739,"sku":"E-AB-62775-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d44b842f-cba8-4679-9492-27a2bd19a6cf.png?v=1710292573","url":"https:\/\/afsbio.com\/products\/gria4-polyclonal-antibody-e-ab-62775","provider":"AFSBio Inc.","version":"1.0","type":"link"}