{"product_id":"grk-4-polyclonal-antibody-bt-ap03826","title":"GRK 4 Polyclonal Antibody - BT-AP03826","description":"\u003cp\u003eGRK 4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03826-20, BT-AP03826-50, BT-AP03826-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GRK4 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser\/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GRK4\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GRK 4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 66583\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P32298; Mouse: O70291\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GRK4; GPRK2L; GPRK4; G protein-coupled receptor kinase 4; G protein-coupled receptor kinase GRK4; ITI1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2868\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240348606643,"sku":"BT-AP03826-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240348639411,"sku":"BT-AP03826-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240348672179,"sku":"BT-AP03826-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_60b8cbce-2966-481e-9b02-28b15f0f82f0.png?v=1769407163","url":"https:\/\/afsbio.com\/products\/grk-4-polyclonal-antibody-bt-ap03826","provider":"AFSBio Inc.","version":"1.0","type":"link"}